Convergent synthesis of carbonic anhydrase inhibiting bi-heterocyclic benzamides: Structure–activity relationship and mechanistic explorations through enzyme inhibition, kinetics, and computational studies
By using a convergent methodology, a novel series of N-arylated 4-yl-benzamides containing a bi-heterocyclic thiazole–triazole core was synthesized, and the structures of these hybrid molecules, 9a–k, were corroborated through spectral analyses. The in vitro studies of these multifunctional molecule...
| Published in: | Journal of Heterocyclic Chemistry |
|---|---|
| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
HeteroCorporation
2021
|
| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100860135&doi=10.1002%2fjhet.4240&partnerID=40&md5=5810164116b32e93ad79702e0679d85d |