Effects of pure and fake honey on glucose and lipid profile in vitro and in vivo study
Honey authenticity is one of the most critical honey trading issues worldwide. Fake honey (FH) represents almost 80% of the honey market in Malaysia. Apart from violating consumer’s rights, FH consists of none of the beneficial nutritional value other than pure honey (PH). Moreover, prolonged consum...
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Malaysian Society of Applied Biology
2020
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2-s2.0-85099852858 Zulkifli M.F.; Samat S.; Azam N.S.M.; Enchang F.K.; Razak A.A.; Hussein F.N.; Ismail W.I.W. Effects of pure and fake honey on glucose and lipid profile in vitro and in vivo study 2020 Malaysian Applied Biology 49 4 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099852858&partnerID=40&md5=33a93886e438d1e0a59e070fc953bc44 Honey authenticity is one of the most critical honey trading issues worldwide. Fake honey (FH) represents almost 80% of the honey market in Malaysia. Apart from violating consumer’s rights, FH consists of none of the beneficial nutritional value other than pure honey (PH). Moreover, prolonged consumption of FH may cause harm to human health. However, data regarding these issues is limited. In this study, both PH and FH were tested using 3T3-L1 adipocytes and in high-fat diet (HFD)-induced obese Sprague Dawley rats. Initially, a physicochemical analysis was performed on both the honey samples according to the Codex Alimentarius Commission and International Honey Commission procedures. After 72 hr, PH significantly reduced lipid accumulation and triglyceride levels in the adipocytes. In the rats, low glucose, cholesterol, and triglyceride levels were significantly detected after orally administered for 16 weeks. Conversely, FH significantly induced higher lipid accumulation and triglyceride levels in adipocytes and excess high blood glucose, cholesterol, and triglyceride levels in rats. The results demonstrated that FH has negative effects on lipid metabolism, and prolonged consumption may cause health complications. Furthermore, prompt actions are required to address this problem. © 2020, Malaysian Society of Applied Biology. All rights reserved. Malaysian Society of Applied Biology 1268643 English Article |
author |
Zulkifli M.F.; Samat S.; Azam N.S.M.; Enchang F.K.; Razak A.A.; Hussein F.N.; Ismail W.I.W. |
spellingShingle |
Zulkifli M.F.; Samat S.; Azam N.S.M.; Enchang F.K.; Razak A.A.; Hussein F.N.; Ismail W.I.W. Effects of pure and fake honey on glucose and lipid profile in vitro and in vivo study |
author_facet |
Zulkifli M.F.; Samat S.; Azam N.S.M.; Enchang F.K.; Razak A.A.; Hussein F.N.; Ismail W.I.W. |
author_sort |
Zulkifli M.F.; Samat S.; Azam N.S.M.; Enchang F.K.; Razak A.A.; Hussein F.N.; Ismail W.I.W. |
title |
Effects of pure and fake honey on glucose and lipid profile in vitro and in vivo study |
title_short |
Effects of pure and fake honey on glucose and lipid profile in vitro and in vivo study |
title_full |
Effects of pure and fake honey on glucose and lipid profile in vitro and in vivo study |
title_fullStr |
Effects of pure and fake honey on glucose and lipid profile in vitro and in vivo study |
title_full_unstemmed |
Effects of pure and fake honey on glucose and lipid profile in vitro and in vivo study |
title_sort |
Effects of pure and fake honey on glucose and lipid profile in vitro and in vivo study |
publishDate |
2020 |
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Malaysian Applied Biology |
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49 |
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4 |
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url |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099852858&partnerID=40&md5=33a93886e438d1e0a59e070fc953bc44 |
description |
Honey authenticity is one of the most critical honey trading issues worldwide. Fake honey (FH) represents almost 80% of the honey market in Malaysia. Apart from violating consumer’s rights, FH consists of none of the beneficial nutritional value other than pure honey (PH). Moreover, prolonged consumption of FH may cause harm to human health. However, data regarding these issues is limited. In this study, both PH and FH were tested using 3T3-L1 adipocytes and in high-fat diet (HFD)-induced obese Sprague Dawley rats. Initially, a physicochemical analysis was performed on both the honey samples according to the Codex Alimentarius Commission and International Honey Commission procedures. After 72 hr, PH significantly reduced lipid accumulation and triglyceride levels in the adipocytes. In the rats, low glucose, cholesterol, and triglyceride levels were significantly detected after orally administered for 16 weeks. Conversely, FH significantly induced higher lipid accumulation and triglyceride levels in adipocytes and excess high blood glucose, cholesterol, and triglyceride levels in rats. The results demonstrated that FH has negative effects on lipid metabolism, and prolonged consumption may cause health complications. Furthermore, prompt actions are required to address this problem. © 2020, Malaysian Society of Applied Biology. All rights reserved. |
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Malaysian Society of Applied Biology |
issn |
1268643 |
language |
English |
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Article |
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scopus |
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Scopus |
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1818940560426139648 |