Characterization and prediction of the non-bonded molecular interactions between racemic ibuprofen and α-lactose monohydrate crystals produced from melt granulation and slow evaporation crystallization
Granulation of racemic ibuprofen (±IBP) and α-lactose monohydrate (ALM) at a slightly lower (±IBP) melting point is an efficient method of binding the active pharmaceutical ingredients (API) and excipient in a binderless condition. However, the co-crystals may be formed from recrystallization of ±IB...
Published in: | Indonesian Journal of Chemistry |
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Main Author: | |
Format: | Article |
Language: | English |
Published: |
Gadjah Mada University
2020
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Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85097240409&doi=10.22146%2fijc.48912&partnerID=40&md5=1281395f1690e10e35918770598b650a |