Characterization and prediction of the non-bonded molecular interactions between racemic ibuprofen and α-lactose monohydrate crystals produced from melt granulation and slow evaporation crystallization

Granulation of racemic ibuprofen (±IBP) and α-lactose monohydrate (ALM) at a slightly lower (±IBP) melting point is an efficient method of binding the active pharmaceutical ingredients (API) and excipient in a binderless condition. However, the co-crystals may be formed from recrystallization of ±IB...

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Bibliographic Details
Published in:Indonesian Journal of Chemistry
Main Author: Lukman Z.; Anuar N.; Bakar N.F.A.; Rahman N.A.
Format: Article
Language:English
Published: Gadjah Mada University 2020
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85097240409&doi=10.22146%2fijc.48912&partnerID=40&md5=1281395f1690e10e35918770598b650a