Design, synthesis, and spasmolytic activity of thiophene-based derivatives via Suzuki cross-coupling reaction of 5-bromothiophene-2-carboxylic acid: Their structural and computational studies

In the current research work, a facile synthesis of a series of novel thiophene-based derivatives of 5-bromothiophene-2- carboxylic acid (1) have been synthesized. All analogs (5a-5e, 10a-10f) were obtained from the coupling reaction of 5-bromothiophene- 2-carboxylic acid (1) and different arylboron...

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Bibliographic Details
Published in:Turkish Journal of Chemistry
Main Author: Rasool N.; Ikram H.M.; Rashid A.; Afzal N.; Hashmi M.A.; Khan M.N.; Khan A.; Imran I.; Rahman H.M.A.; Shah S.A.A.
Format: Article
Language:English
Published: TUBITAK 2020
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85096172227&doi=10.3906%2fKIM-1911-51&partnerID=40&md5=52e898fd2ca2010e33ab2812224eddcf