Emodin derivatives as multi-target-directed ligands inhibiting monoamine oxidase and antagonizing vasopressin V1Areceptors
The brain neurotransmitter level is associated with the pathology of various neurodegenerative diseases, and age-dependent increase in the blood level of vasopressin, human brain monoamine oxidase (hMAO) level, oxidative stress, and imbalance in aminergic signaling are common disease-modifying facto...
Published in: | ACS Omega |
---|---|
Main Author: | Paudel P.; Shrestha S.; Park S.E.; Seong S.H.; Fauzi F.M.; Jung H.A.; Choi J.S. |
Format: | Article |
Language: | English |
Published: |
American Chemical Society
2020
|
Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85094199237&doi=10.1021%2facsomega.0c03649&partnerID=40&md5=ac8208adaa265c74f1b153436d05ffe0 |
Similar Items
-
Monoamine oxidase inhibition by major tanshinones from salvia miltiorrhiza and selective muscarinic acetylcholine m4 receptor antagonism by tanshinone i
by: Prajapati R.; Park S.E.; Seong S.H.; Paudel P.; Fauzi F.M.; Jung H.A.; Choi J.S.
Published: (2021) -
Semicarbazones, thiosemicarbazone, thiazole and oxazole analogues as monoamine oxidase inhibitors: Synthesis, characterization, biological evaluation, molecular docking, and kinetic studies
by: Qazi S.U.; Naz A.; Hameed A.; Osra F.A.; Jalil S.; Iqbal J.; Shah S.A.A.; Mirza A.Z.
Published: (2021) -
Synthesis, characterization, monoamine oxidase inhibition, molecular docking and dynamic simulations of novel 2,1-benzothiazine-2,2-dioxide derivatives
by: Ahmad S.; Zaib S.; Jalil S.; Shafiq M.; Ahmad M.; Sultan S.; Iqbal M.; Aslam S.; Iqbal J.
Published: (2018) -
Natural Bioactive Compounds Targeting NADPH Oxidase Pathway in Cardiovascular Diseases
by: Sofiullah S.S.M.; Murugan D.D.; Muid S.A.; Seng W.Y.; Kadir S.Z.S.A.; Abas R.; Ridzuan N.R.A.; Zamakshshari N.H.; Woon C.K.
Published: (2023) -
Synthesis, X-ray crystal and monoamine oxidase inhibitory activity of 4,6-dihydrobenzo[c]pyrano[2,3-e][1,2]thiazine 5,5-dioxides: In vitro studies and docking analysis
by: Ahmad S.; Jalil S.; Zaib S.; Aslam S.; Ahmad M.; Rasul A.; Arshad M.N.; Sultan S.; Hameed A.; Asiri A.M.; Iqbal J.
Published: (2019)