Emodin derivatives as multi-target-directed ligands inhibiting monoamine oxidase and antagonizing vasopressin V1Areceptors

The brain neurotransmitter level is associated with the pathology of various neurodegenerative diseases, and age-dependent increase in the blood level of vasopressin, human brain monoamine oxidase (hMAO) level, oxidative stress, and imbalance in aminergic signaling are common disease-modifying facto...

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Bibliographic Details
Published in:ACS Omega
Main Author: Paudel P.; Shrestha S.; Park S.E.; Seong S.H.; Fauzi F.M.; Jung H.A.; Choi J.S.
Format: Article
Language:English
Published: American Chemical Society 2020
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85094199237&doi=10.1021%2facsomega.0c03649&partnerID=40&md5=ac8208adaa265c74f1b153436d05ffe0