Synthesis of benzimidazole–based analogs as anti alzheimer’s disease compounds and their molecular docking studies

We synthesized 10 analogs of benzimidazole-based thiosemicarbazide 1 (a–j) and 13 benzimidazole-based Schiff bases 2 (a–m), and characterized by various spectroscopic techniques and evaluated in vitro for acetylcholinesterase (AchE) and butyrylcholinesterase (BchE) inhibition activities. All the syn...

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Bibliographic Details
Published in:Molecules
Main Author: Adalat B.; Rahim F.; Taha M.; Alshamrani F.J.; Anouar E.H.; Uddin N.; Shah S.A.A.; Ali Z.; Zakaria Z.A.
Format: Article
Language:English
Published: MDPI AG 2020
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85093694209&doi=10.3390%2fmolecules25204828&partnerID=40&md5=e67ece50533c78c90d8a2924bfca506e