Enhanced selective cytotoxicity of doxorubicin to breast cancer cells by methoxypolyethylene glycol conjugation via a novel beta-thiopropanamide linker
Doxorubicin (DOX) is a chemotherapeutic agent that suffers from severe adverse effects due to non-selective cell cytotoxicity. This study designs a novel beta-thiopropanamide linker (A) which conjugates DOX with methoxypolyethylene glycol (mPEG) to sustain systemic drug release, and to promote cance...
| Published in: | European Polymer Journal |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Elsevier Ltd
2020
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85092526437&doi=10.1016%2fj.eurpolymj.2020.110056&partnerID=40&md5=3a7f30d6e25c7ee9733a0e1c07b39d04 |