Isatin based thiosemicarbazide derivatives as potential inhibitor of α-glucosidase, synthesis and their molecular docking study
A new series of isatin based thiosemicarbazide derivatives 1–15 were synthesized and characterized by 1H NMR, 13C NMR and HR-EIMS. The synthetic derivatives were evaluated for α-glucosidase inhibitory potential. All compounds showed excellent α-glucosidase inhibitory potential having IC50 values ran...
Published in: | Journal of Molecular Structure |
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Main Author: | |
Format: | Article |
Language: | English |
Published: |
Elsevier B.V.
2020
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Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85088267274&doi=10.1016%2fj.molstruc.2020.128922&partnerID=40&md5=38383f852ae51aba7a7f976151ae1938 |