Synthesis, in vitro urease inhibitory potential and molecular docking study of benzofuran-based-thiazoldinone analogues

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Synthesis, in vitro urease inhibitory potential and molecular docking study of benzofuran-based-thiazoldinone analogues

In continuation of our work on enzyme inhibition, the benzofuran-based-thiazoldinone analogues (1–14) were synthesized, characterized by HREI-MS, 1H and 13CNMR and evaluated for urease inhibition. Compounds 1–14 exhibited a varying degree of urease inhibitory activity with IC50 values between 1.2 ±...

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Bibliographic Details
Published in:	Scientific Reports
Main Author:	Taha M.; Rahim F.; Ullah H.; Wadood A.; Farooq R.K.; Shah S.A.A.; Nawaz M.; Zakaria Z.A.
Format:	Article
Language:	English
Published:	Nature Research 2020
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85087130142&doi=10.1038%2fs41598-020-67414-7&partnerID=40&md5=ae14b271a5853b4cf1b499a499b65f3b

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