Synthesis, in vitro urease inhibitory potential and molecular docking study of benzofuran-based-thiazoldinone analogues
In continuation of our work on enzyme inhibition, the benzofuran-based-thiazoldinone analogues (1–14) were synthesized, characterized by HREI-MS, 1H and 13CNMR and evaluated for urease inhibition. Compounds 1–14 exhibited a varying degree of urease inhibitory activity with IC50 values between 1.2 ±...
| Published in: | Scientific Reports |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Nature Research
2020
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85087130142&doi=10.1038%2fs41598-020-67414-7&partnerID=40&md5=ae14b271a5853b4cf1b499a499b65f3b |