Discovery of Dual Inhibitors of Acetyl and Butrylcholinesterase and Antiproliferative Activity of 1,2,4-Triazole-3-thiol: Synthesis and In Silico Molecular Study
The aim of this current study is to discover effective acetyl and butrylcholinesterase enzyme inhibitors. A concise library of S-alkylated/arylated-4-ethyl-5-(4-methoxyphenyl)-4H-1,2,4-triazole-3-thiols 5–18 was synthesized by using a multistep reaction sequence. The compounds were characterized by...
Published in: | ChemistrySelect |
---|---|
Main Author: | |
Format: | Article |
Language: | English |
Published: |
Wiley-Blackwell
2020
|
Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85087042710&doi=10.1002%2fslct.201904905&partnerID=40&md5=d590998bb08f0019fbf72c99d821dd99 |