Design, synthesis and computational studies of N-(substituted-phenyl)-4-(4-phenyl-1-piperazinyl)butanamides as potent anti-melanogenic and tyrosinase inhibitors

This manuscript describes the synthesis of some new N-(substituted-phenyl)-4-(4-phenyl-1-piperazinyl)butanamides (5a-c) through a facile bi-step strategy. The structures of these compounds were corroborated by their IR, EI-MS, 1H NMR, 13C NMR spectra along with CHN analysis data. The results of Mush...

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Bibliographic Details
Published in:Journal of Molecular Structure
Main Author: Raza H.; Abbasi M.A.; Rehman A.-U.; Siddiqui S.Z.; Hassan M.; Shah S.A.A.; Shahid M.; Hong H.; Seo S.-Y.
Format: Article
Language:English
Published: Elsevier B.V. 2020
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85081681057&doi=10.1016%2fj.molstruc.2020.127969&partnerID=40&md5=edf68b9124e195ebc612a7af38410c4f