Synthesis of new S-substituted derivatives of 5-[3-(1H-indol-3-yl) propyl]-1, 3, 4-oxadiazol-2-ylhydrosulfide as suitable antibacterial and anticancer agents with moderate cytotoxicity
In the study presented here, the nucleophilic substitution reaction of 5-[3-(1H-indol-3-yl)propyl]-1,3,4-oxadiazol-2-ylhydrosulfide was carried out with different alkyl/aralkyl halides (5a-r) to form its different S-substituted derivatives (6a-r), as depicted in scheme 1. The structural confirmation...
Published in: | Pakistan Journal of Pharmaceutical Sciences |
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Main Author: | |
Format: | Article |
Language: | English |
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Pakistan Journal of Pharmaceutical Sciences
2019
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Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85077920909&doi=10.36721%2fPJPS.2019.32.6.REG.2585-2597.1&partnerID=40&md5=e660b161b0906e2a00c51faaad2e6083 |