Mitragynine, an euphoric compound inhibits hERG1a/1b channel current and upregulates the complexation of hERG1a-Hsp90 in HEK293-hERG1a/1b cells
Mitragyna speciosa Korth (M. speciosa) has been widely used as a recreational product, however, there are growing concerns on the abuse potentials and toxicity of the plant. Several poisoning and fatal cases involving kratom and mitragynine have been reported but the underlying causes remain unclear...
| Published in: | Scientific Reports |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Nature Research
2019
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85077165762&doi=10.1038%2fs41598-019-56106-6&partnerID=40&md5=91025b95a9f9d5b0c5714a3795ec9692 |