Synthesis of new 2-{2,3-dihydro-1,4-benzodioxin-6-yl[(4‑methylphenyl) sulfonyl]amino}-N-(un/substituted-phenyl) acetamides as α-glucosidase and acetylcholinesterase inhibitors and their in silico study

The aim of the present research work was to investigate the enzyme inhibitory potential of some new sulfonamides having benzodioxane and acetamide moieties. The synthesis was started by the reaction of N-2,3-dihydrobenzo[1,4]-dioxin-6-amine (1) with 4-methylbenzenesulfonyl chloride (2) in the presen...

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Bibliographic Details
Published in:Brazilian Journal of Pharmaceutical Sciences
Main Author: Abbasi M.A.; Riaz S.; Aziz-Ur-rehman; Siddiqui S.Z.; Shah S.A.A.; Ashraf M.; Lodhi M.A.; Khan F.A.
Format: Article
Language:English
Published: Faculdade de Ciencias Farmaceuticas (Biblioteca) 2019
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85073287972&doi=10.1590%2fs2175-97902019000117032&partnerID=40&md5=a167d2a6310710b18ecf2c2eabe0340e