Synthesis of new 2-{2,3-dihydro-1,4-benzodioxin-6-yl[(4‑methylphenyl) sulfonyl]amino}-N-(un/substituted-phenyl) acetamides as α-glucosidase and acetylcholinesterase inhibitors and their in silico study
The aim of the present research work was to investigate the enzyme inhibitory potential of some new sulfonamides having benzodioxane and acetamide moieties. The synthesis was started by the reaction of N-2,3-dihydrobenzo[1,4]-dioxin-6-amine (1) with 4-methylbenzenesulfonyl chloride (2) in the presen...
Published in: | Brazilian Journal of Pharmaceutical Sciences |
---|---|
Main Author: | |
Format: | Article |
Language: | English |
Published: |
Faculdade de Ciencias Farmaceuticas (Biblioteca)
2019
|
Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85073287972&doi=10.1590%2fs2175-97902019000117032&partnerID=40&md5=a167d2a6310710b18ecf2c2eabe0340e |