Ticagrelor induces paraoxonase-1 (PON1) and better protects hypercholesterolemic mice against atherosclerosis compared to clopidogrel

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Ticagrelor induces paraoxonase-1 (PON1) and better protects hypercholesterolemic mice against atherosclerosis compared to clopidogrel

Ticagrelor (TIC), a P2Y purinoceptor 12 (P2Y12)-receptor antagonist, has been widely used to treat patients with acute coronary syndrome. Although animal studies suggest that TIC protects against atherosclerosis, it remains unknown whether it does so through its potent platelet inhibition or through...

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Bibliographic Details
Published in:	PLoS ONE
Main Author:	Halim H.; Pinkaew D.; Chunhacha P.; Sinthujaroen P.; Thiagarajan P.; Fujise K.
Format:	Article
Language:	English
Published:	Public Library of Science 2018
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85068896088&doi=10.1371%2fjournal.pone.0218934&partnerID=40&md5=29af71b69c8eb7b2ecc963c0b96ad4bc

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