Ticagrelor induces paraoxonase-1 (PON1) and better protects hypercholesterolemic mice against atherosclerosis compared to clopidogrel
Ticagrelor (TIC), a P2Y purinoceptor 12 (P2Y12)-receptor antagonist, has been widely used to treat patients with acute coronary syndrome. Although animal studies suggest that TIC protects against atherosclerosis, it remains unknown whether it does so through its potent platelet inhibition or through...
| Published in: | PLoS ONE |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science
2018
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85068896088&doi=10.1371%2fjournal.pone.0218934&partnerID=40&md5=29af71b69c8eb7b2ecc963c0b96ad4bc |