Design, synthesis and biological potential of 5-(2-amino-6-(3/4-bromophenyl)pyrimidin-4-yl)benzene-1,3-diol scaffolds as promising antimicrobial and anticancer agents

Background: A series of 5-(2-amino-6-(3/4-bromophenyl)pyrimidin-4-yl)benzene-1,3-diol scaffolds was synthesized by Claisen-Schmidt condensation and characterized by NMR, IR, Mass and elemental analyses. Methods: The synthesized pyrimidine scaffolds were screened for their antimicrobial activity by t...

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Bibliographic Details
Published in:Mini-Reviews in Medicinal Chemistry
Main Author: Kumar S.; Narasimhan B.; Lim S.M.; Ramasamy K.; Mani V.; Ali Shah S.A.
Format: Article
Language:English
Published: Bentham Science Publishers 2019
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85068842264&doi=10.2174%2f1389557518666181009141924&partnerID=40&md5=15282a5b736b19b3d0801edc3433f426