Pantoprazole to Prevent Gastroduodenal Events in Patients Receiving Rivaroxaban and/or Aspirin in a Randomized, Double-Blind, Placebo-Controlled Trial

Pantoprazole to Prevent Gastroduodenal Events in Patients Receiving Rivaroxaban and/or Aspirin in a Randomized, Double-Blind, Placebo-Controlled Trial

Background & Aims: Antiplatelets and anticoagulants are associated with increased upper gastrointestinal bleeding. We evaluated whether proton pump inhibitor therapy could reduce this risk. Methods: We performed a 3 × 2 partial factorial double-blind trial of 17,598 participants with stable card...

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Published in:Gastroenterology
Main Author: Moayyedi P.; Eikelboom J.W.; Bosch J.; Connolly S.J.; Dyal L.; Shestakovska O.; Leong D.; Anand S.S.; Störk S.; Branch K.R.H.; Bhatt D.L.; Verhamme P.B.; O'Donnell M.; Maggioni A.P.; Lonn E.M.; Piegas L.S.; Ertl G.; Keltai M.; Cook Bruns N.; Muehlhofer E.; Dagenais G.R.; Kim J.-H.; Hori M.; Steg P.G.; Hart R.G.; Diaz R.; Alings M.; Widimsky P.; Avezum A.; Probstfield J.; Zhu J.; Liang Y.; Lopez-Jaramillo P.; Kakkar A.; Parkhomenko A.N.; Ryden L.; Pogosova N.; Dans A.; Lanas F.; Commerford P.J.; Torp-Pedersen C.; Guzik T.; Vinereanu D.; Tonkin A.M.; Lewis B.S.; Felix C.; Yusoff K.; Metsarinne K.; Fox K.A.A.; Yusuf S.
Format: Article
Language:English
Published: W.B. Saunders 2019
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85068311091&doi=10.1053%2fj.gastro.2019.04.041&partnerID=40&md5=3f22980e1e5c738d103e63b6848c7318

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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85068311091&doi=10.1053%2fj.gastro.2019.04.041&partnerID=40&md5=3f22980e1e5c738d103e63b6848c7318

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