Oxindole-based chalcones: synthesis and their activity against glycation of proteins

Diabetes mellitus, a metabolic disorder, is characterized by a substantial hyperglycaemia. Prevalence of hyperglycaemia for longer period of time can cause nonenzymatic condensation of sugar in blood with amino group of protein and give rise to advanced glycation end products (AGEs). AGEs play a maj...

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Bibliographic Details
Published in:Medicinal Chemistry Research
Main Author: Khan A.; Khan A.; Farooq U.; Taha M.; Shah S.A.A.; Halim S.A.; Akram A.; Khan M.Z.; Jan A.K.; Al-Harrasi A.
Format: Article
Language:English
Published: Birkhauser Boston 2019
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85064650678&doi=10.1007%2fs00044-019-02345-1&partnerID=40&md5=66c278e82295bf402da68728691f8168