Synthesis of novel N-(1,3-thiazol-2-yl)benzamide clubbed oxadiazole scaffolds: Urease inhibition, Lipinski rule and molecular docking analyses
Present work aimed to synthesize some unique bi-heterocyclic benzamides as lead compounds for the in vitro inhibition of urease enzyme, followed by in silico studies. These targeted benzamides were synthesized in good yields through a multi-step protocol and their struct...
Published in: | Bioorganic Chemistry |
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Main Author: | |
Format: | Article |
Language: | English |
Published: |
Academic Press Inc.
2019
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Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85054810473&doi=10.1016%2fj.bioorg.2018.10.018&partnerID=40&md5=5ed095fef911fb73da03a549a6c3c914 |