Synthesis, β-Glucuronidase Inhibition, and Molecular Docking Studies of 1,2,4-Triazole Hydrazones
A series of 1,2,4-triazole hydrazones 1–25 has been synthesized and characterized using different spectroscopic techniques including FT-IR, 1H-NMR, and ESI MS spectrometry. The synthetic derivatives were evaluated for their β-glucuronidase enzyme inhibition properties. Among them, 17 compounds demon...
Published in: | Journal of the Iranian Chemical Society |
---|---|
Main Author: | Jamil W.; Kumari D.; Taha M.; Khan M.N.; Baharudin M.S.; Ali M.; Kanwal M.; Lashari M.S.; Khan K.M. |
Format: | Article |
Language: | English |
Published: |
Springer Verlag
2018
|
Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85053018316&doi=10.1007%2fs13738-018-1433-9&partnerID=40&md5=5cc1c5bdf556de18241cd60c45f097c1 |
Similar Items
-
Synthesis, β-glucuronidase inhibition and molecular docking studies of cyano-substituted bisindole hydrazone hybrids
by: Abid O.; Imran S.; Taha M.; Ismail N.H.; Jamil W.; Kashif S.M.; Khan K.M.; Yusoff J.
Published: (2021) -
Synthesis, β-glucuronidase inhibition and molecular docking studies of hybrid bisindole-thiosemicarbazides analogs
by: Taha M.; Ismail N.H.; Imran S.; Rahim F.; Wadood A.; Khan H.; Ullah H.; Salar U.; Khan K.M.
Published: (2016) -
Synthesis of indole analogs as potent β-glucuronidase inhibitors
by: Baharudin M.S.; Taha M.; Imran S.; Ismail N.H.; Rahim F.; Javid M.T.; Khan K.M.; Ali M.
Published: (2017) -
Identification of bisindolylmethane-hydrazone hybrids as novel inhibitors of β-glucuronidase, DFT, and in silico SAR intimations
by: Taha M.; Ismail N.H.; Imran S.; Anouar E.H.; Ali M.; Jamil W.; Uddin N.; Kashif S.M.
Published: (2016) -
Synthesis: Small library of hybrid scaffolds of benzothiazole having hydrazone and evaluation of their β-glucuronidase activity
by: Taha M.; Arbin M.; Ahmat N.; Imran S.; Rahim F.
Published: (2018)