Synthesis, β-Glucuronidase Inhibition, and Molecular Docking Studies of 1,2,4-Triazole Hydrazones

A series of 1,2,4-triazole hydrazones 1–25 has been synthesized and characterized using different spectroscopic techniques including FT-IR, 1H-NMR, and ESI MS spectrometry. The synthetic derivatives were evaluated for their β-glucuronidase enzyme inhibition properties. Among them, 17 compounds demon...

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Bibliographic Details
Published in:Journal of the Iranian Chemical Society
Main Author: Jamil W.; Kumari D.; Taha M.; Khan M.N.; Baharudin M.S.; Ali M.; Kanwal M.; Lashari M.S.; Khan K.M.
Format: Article
Language:English
Published: Springer Verlag 2018
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85053018316&doi=10.1007%2fs13738-018-1433-9&partnerID=40&md5=5cc1c5bdf556de18241cd60c45f097c1