Synthesis of some new propanamide derivatives bearing 4-piperidinyl-1,3,4-oxadiazole, and their evaluation as promising anticancer agents

Purpose: To sequentially synthesize piperidine-4-carboxylic acid ethyl ester-appended 1,3,4-oxadiazole hybrids and to evaluate them as anticancer agents. Methods: Ethyl 1-[(4-methylphenyl)sulfonyl]-4-piperidinecarboxylate (1) was synthesized from 4-methylbenzenesulfonylchloride (a) and ethyl 4-piper...

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Bibliographic Details
Published in:Tropical Journal of Pharmaceutical Research
Main Author: Aziz-Ur-Rehman; Ahtzaz N.; Abbasi M.A.; Siddiqui S.Z.; Saleem S.; Manzoor S.; Iqbal J.; Virk N.A.; Chohan T.A.; Shah S.A.A.
Format: Article
Language:English
Published: University of Benin 2018
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049457291&doi=10.4314%2ftjpr.v17i6.22&partnerID=40&md5=759d1d61e518baf55c66c92221487500