Synthesis, characterization, monoamine oxidase inhibition, molecular docking and dynamic simulations of novel 2,1-benzothiazine-2,2-dioxide derivatives

In this research work, we report the synthesis and biological evaluation of two new series of 1-benzyl-4-(benzylidenehydrazono)-3,4-dihydro-1H-benzo[c] [1,2]thiazine 2,2-dioxides and 1-benzyl-4-((1-phenylethylidene)hydrazono)-3,4-dihydro-1H-benzo[c][1,2]thiazine 2,2-dioxides. The synthetic plan invo...

Full description

Bibliographic Details
Published in:Bioorganic Chemistry
Main Author: Ahmad S.; Zaib S.; Jalil S.; Shafiq M.; Ahmad M.; Sultan S.; Iqbal M.; Aslam S.; Iqbal J.
Format: Article
Language:English
Published: Academic Press Inc. 2018
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049424235&doi=10.1016%2fj.bioorg.2018.04.012&partnerID=40&md5=44ba3251381bd0c20d420dc140ca87bd