Synthesis, α-glucosidase inhibition and molecular docking study of coumarin based derivatives
We have synthesized seventeen Coumarin based derivatives (1–17), characterized by 1HNMR, 13CNMR and EI-MS and evaluated for α-glucosidase inhibitory potential. Among the series, all derivatives exhibited outstanding α-glucosidase inhibition with IC50 values ranging between 1.10 ± 0.01 and 36.46 ± 0....
| Published in: | Bioorganic Chemistry |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Academic Press Inc.
2018
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85042298379&doi=10.1016%2fj.bioorg.2018.01.033&partnerID=40&md5=5c35beb970165c041387e80b318fdd17 |