Intraocular pressure lowering effect and structure-activity relationship of imidazo[1,2-a]benzimidazole and pyrimido[1,2-a]benzimidazole compounds in ocular normotensive rats: Insight on possible link with hypotensive activity
In an effort to find new ocular hypotensive drug candidates, a total of 27 condensed benzimidazoles based compounds were screened. This study was done in normotensive rats and rebound tonometry was used to estimate IOP. All compounds were topically applied as a single drop, unilaterally, at 3 differ...
| Published in: | European Journal of Pharmaceutical Sciences |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Elsevier B.V.
2018
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85039419476&doi=10.1016%2fj.ejps.2017.12.015&partnerID=40&md5=217529effc66c759005dd8a9bc2b8792 |