Synthesis of piperazine sulfonamide analogs as diabetic-II inhibitors and their molecular docking study

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Synthesis of piperazine sulfonamide analogs as diabetic-II inhibitors and their molecular docking study

Piperazine Sulfonamide analogs (1–19) have been synthesized, characterized by different spectroscopic techniques and evaluated for α-amylase Inhibition. Analogs 1–19 exhibited a varying degree of α-amylase inhibitory activity with IC50 values ranging in between 1.571 ± 0.05 to 3.98 ± 0.397 μM when c...

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Bibliographic Details
Published in:	European Journal of Medicinal Chemistry
Main Author:	Taha M.; Irshad M.; Imran S.; Chigurupati S.; Selvaraj M.; Rahim F.; Ismail N.H.; Nawaz F.; Khan K.M.
Format:	Article
Language:	English
Published:	Elsevier Masson s.r.l. 2017
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85032929001&doi=10.1016%2fj.ejmech.2017.10.028&partnerID=40&md5=dd50c9fcba76ab67831ba7f3d8094e0c

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