Synthesis of piperazine sulfonamide analogs as diabetic-II inhibitors and their molecular docking study
Piperazine Sulfonamide analogs (1–19) have been synthesized, characterized by different spectroscopic techniques and evaluated for α-amylase Inhibition. Analogs 1–19 exhibited a varying degree of α-amylase inhibitory activity with IC50 values ranging in between 1.571 ± 0.05 to 3.98 ± 0.397 μM when c...
| Published in: | European Journal of Medicinal Chemistry |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Elsevier Masson s.r.l.
2017
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85032929001&doi=10.1016%2fj.ejmech.2017.10.028&partnerID=40&md5=dd50c9fcba76ab67831ba7f3d8094e0c |