3,4-Dimethoxybenzohydrazide derivatives as antiulcer: Molecular modeling and density functional studies
3,4-Dimethoxybenzohydrazide derivatives (1–25) have been synthesized and evaluated for their urease inhibitory potential. Among the series, compounds 2, 3, 4 and 5 with IC50 values 12.61 ± 0.07, 18.24 ± 0.14, 19.22 ± 0.21, and 8.40 ± 0.05 µM, respectively, showed excellent urease inhibitory potentia...
| Published in: | Bioorganic Chemistry |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Academic Press Inc.
2017
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85030837914&doi=10.1016%2fj.bioorg.2017.10.004&partnerID=40&md5=055d13c0412cdc382630942a70265216 |