Exposure to electrophiles impairs reactive persulfide-dependent redox signaling in neuronal cells

Electrophiles such as methylmercury (MeHg) affect cellular functions by covalent modification with endogenous thiols. Reactive persulfide species were recently reported to mediate antioxidant responses and redox signaling because of their strong nucleophilicity. In this study, we used MeHg as an env...

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Bibliographic Details
Published in:Chemical Research in Toxicology
Main Author: Ihara H.; Kasamatsu S.; Kitamura A.; Nishimura A.; Tsutsuki H.; Ida T.; Ishizaki K.; Toyama T.; Yoshida E.; Hamid H.A.; Jung M.; Matsunaga T.; Fujii S.; Sawa T.; Nishida M.; Kumagai Y.; Akaike T.
Format: Article
Language:English
Published: American Chemical Society 2017
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85030615989&doi=10.1021%2facs.chemrestox.7b00120&partnerID=40&md5=8ac60f758572daaa1584a02c4996dada