Synthesis and study of the α-amylase inhibitory potential of thiadiazole quinoline derivatives

α-Amylase is a target for type-2 diabetes mellitus treatment. However, small molecule inhibitors of α-amylase are currently scarce. In the course of developing small molecule α-amylase inhibitors, we designed and synthesized thiadiazole quinoline analogs (1−30), characterized by different spectrosco...

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Bibliographic Details
Published in:Bioorganic Chemistry
Main Author: Taha M.; Tariq Javid M.; Imran S.; Selvaraj M.; Chigurupati S.; Ullah H.; Rahim F.; Khan F.; Islam Mohammad J.; Mohammed Khan K.
Format: Article
Language:English
Published: Academic Press Inc. 2017
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85027553854&doi=10.1016%2fj.bioorg.2017.08.003&partnerID=40&md5=0371c534d97f8eb662187c1a95a5e868