Anticholinesterase activity of octa peptides related to human histatin 8: In-silico drug design and In-vitro
Objective: To evaluate the octapeptides related to human histatin 8 by in-silico and in-vitro studies. Method: Schrodinger, LLC and Ellman’s method. Results: The compound HH1 and HH2 was found to be potent docking score of −9.494 and −7.401 against acetylcholinesterase (AChE) enzyme. The IC50 value...
| Published in: | Asian Journal of Pharmaceutical and Clinical Research |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Innovare Academics Sciences Pvt. Ltd
2017
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85020908052&doi=10.22159%2fajpcr.2017.v10i6.17697&partnerID=40&md5=ad0d559ad885e10cf0a874b79d863c45 |