Ciproxifan improves cholinergic transmission, attenuates neuroinflammation and oxidative stress but does not reduce amyloid level in transgenic mice

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Ciproxifan improves cholinergic transmission, attenuates neuroinflammation and oxidative stress but does not reduce amyloid level in transgenic mice

Aim The present study is aimed to investigate the ability of ciproxifan, a histamine H3 receptor antagonist to inhibit β-amyloid (Aβ)-induced neurotoxicity in SK-N-SH cells and APP transgenic mouse model. Materials and methods In vitro studies was designed to evaluate the neuroprotective effects of...

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Bibliographic Details
Published in:	Life Sciences
Main Author:	Mani V.; Jaafar S.M.; Azahan N.S.M.; Ramasamy K.; Lim S.M.; Ming L.C.; Majeed A.B.A.
Format:	Article
Language:	English
Published:	Elsevier Inc. 2017
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85019189904&doi=10.1016%2fj.lfs.2017.05.013&partnerID=40&md5=b9c85457d77c002934db26bcd6e05186

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