Ciproxifan improves cholinergic transmission, attenuates neuroinflammation and oxidative stress but does not reduce amyloid level in transgenic mice
Aim The present study is aimed to investigate the ability of ciproxifan, a histamine H3 receptor antagonist to inhibit β-amyloid (Aβ)-induced neurotoxicity in SK-N-SH cells and APP transgenic mouse model. Materials and methods In vitro studies was designed to evaluate the neuroprotective effects of...
| Published in: | Life Sciences |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Elsevier Inc.
2017
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85019189904&doi=10.1016%2fj.lfs.2017.05.013&partnerID=40&md5=b9c85457d77c002934db26bcd6e05186 |