Synthesis and in silico study of 2-furyl(4-{4-[(substituted)sulfonyl]benzyl}-1-piperazinyl)methanone derivatives as suitable therapeutic agents

In the study presented here, a new series of 2-furyl(4-{4-[(substituted)sulfonyl]benzyl}-1-piperazinyl)methanone derivatives was targeted. The synthesis was initiated by the treatment of different secondary amines (1a-h) with 4-bromomethylbenzenesulfonyl chloride (2) to obtain various 1-{[4-(bromome...

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Bibliographic Details
Published in:Brazilian Journal of Pharmaceutical Sciences
Main Author: Hussain G.; Abbasi M.A.; Aziz-ur-Rehman; Siddiqui S.Z.; Shah S.A.A.; Ashraf M.; Qurat-ul-Ain; Ahmad I.; Malik R.; Lodhi M.A.; Khan F.A.; Shahid M.; Fatima H.
Format: Article
Language:English
Published: Faculdade de Ciencias Farmaceuticas (Biblioteca) 2017
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85018664413&doi=10.1590%2fs2175-97902017000115237&partnerID=40&md5=026c95a5757de64b42aa338b0846c966