Carbohydrazones as new class of carbonic anhydrase inhibitors: Synthesis, kinetics, and ligand docking studies

Discovery and development of carbonic anhydrase inhibitors is crucial for their clinical use as antiepileptic, diurectic and antiglaucoma agents. Keeping this in mind, we have synthesized carbohydrazones 1–27 and evaluated them for their in vitro carbonic anhydrase inhibitory potential. Out of twent...

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Bibliographic Details
Published in:Bioorganic Chemistry
Main Author: Iqbal S.; Saleem M.; Azim M.K.; Taha M.; Salar U.; Khan K.M.; Perveen S.; Choudhary M.I.
Format: Article
Language:English
Published: Academic Press Inc. 2017
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85017101492&doi=10.1016%2fj.bioorg.2017.03.014&partnerID=40&md5=7b441424767eec38cc62eeac138faf38