Reduction of oxidative-nitrosative stress underlies anticataract effect of topically applied tocotrienol in streptozotocin-induced diabetic rats

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Reduction of oxidative-nitrosative stress underlies anticataract effect of topically applied tocotrienol in streptozotocin-induced diabetic rats

Cataract, a leading cause of blindness, is of special concern in diabetics as it occurs at earlier onset. Polyol accumulation and increased oxidative-nitrosative stress in cataractogenesis are associated with NFκB activation, iNOS expression, ATP depletion, loss of ATPase functions, calpain activati...

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Bibliographic Details
Published in:	PLoS ONE
Main Author:	Nasir N.A.A.; Agarwal R.; Kadir S.H.S.A.; Vasudevan S.; Tripathy M.; Iezhitsa I.; Daher A.M.; Ibrahim M.I.; Ismail N.M.
Format:	Article
Language:	English
Published:	Public Library of Science 2017
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85016318980&doi=10.1371%2fjournal.pone.0174542&partnerID=40&md5=ad23ac5d9637ceadd9c6f57e8e337ecb

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