Molecular hybridization conceded exceptionally potent quinolinyl-oxadiazole hybrids through phenyl linked thiosemicarbazide antileishmanial scaffolds: In silico validation and SAR studies

The high potential of quinoline containing natural products and their derivatives in medicinal chemistry led us to discover a novel series of compounds 6–23 based on the concept of molecular hybridization. Most of the synthesized analogues exhibited potent leishmanicidal potential. The most potent c...

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Bibliographic Details
Published in:Bioorganic Chemistry
Main Author: Taha M.; Ismail N.H.; Ali M.; Rashid U.; Imran S.; Uddin N.; Khan K.M.
Format: Article
Language:English
Published: Academic Press Inc. 2017
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85013078177&doi=10.1016%2fj.bioorg.2017.02.005&partnerID=40&md5=e5c710c4b1205f0ad97509871f6d5cee