Smart nanocrystals of artemether: Fabrication, characterization, and comparative in vitro and in vivo antimalarial evaluation

Artemether (ARTM) is a very effective antimalarial drug with poor solubility and consequently low bioavailability. Smart nanocrystals of ARTM with particle size of 161±1.5 nm and polydispersity index of 0.172±0.01 were produced in <1 hour using a wet milling technology, Dena® DM-100. The crystall...

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Bibliographic Details
Published in:Drug Design, Development and Therapy
Main Author: Shah S.M.H.; Ullah F.; Khan S.; Shah S.M.M.; de Matas M.; Hhussain Z.; Minhas M.U.; AabdEel-Salam N.M.; Aassi K.H.; Iisreb M.
Format: Article
Language:English
Published: Dove Medical Press Ltd. 2016
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85003698530&doi=10.2147%2fDDDT.S114962&partnerID=40&md5=2d40ddbc82d921a163dcfb60a26526ed

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