Smart nanocrystals of artemether: Fabrication, characterization, and comparative in vitro and in vivo antimalarial evaluation
Artemether (ARTM) is a very effective antimalarial drug with poor solubility and consequently low bioavailability. Smart nanocrystals of ARTM with particle size of 161±1.5 nm and polydispersity index of 0.172±0.01 were produced in <1 hour using a wet milling technology, Dena® DM-100. The crystall...
| Published in: | Drug Design, Development and Therapy |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press Ltd.
2016
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85003698530&doi=10.2147%2fDDDT.S114962&partnerID=40&md5=2d40ddbc82d921a163dcfb60a26526ed |