Biology-oriented drug synthesis (BIODS): In vitro β-glucuronidase inhibitory and in silico studies on 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl aryl carboxylate derivatives

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Biology-oriented drug synthesis (BIODS): In vitro β-glucuronidase inhibitory and in silico studies on 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl aryl carboxylate derivatives

Current study is based on the biology-oriented drug synthesis (BIODS) of 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl aryl carboxylate derivatives 1–26, by treating metronidazole with different aryl and hetero-aryl carboxylic acids in the presence of 1,1'-carbonyl diimidazole (CDI) as a coupling...

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Bibliographic Details
Published in:	European Journal of Medicinal Chemistry
Main Author:	Salar U.; Khan K.M.; Taha M.; Ismail N.H.; Ali B.; Qurat-ul-Ain; Perveen S.; Ghufran M.; Wadood A.
Format:	Article
Language:	English
Published:	Elsevier Masson SAS 2017
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-84998812010&doi=10.1016%2fj.ejmech.2016.11.031&partnerID=40&md5=937e8fecaed1bd9be8889e93bcbc9b85

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