Biology-oriented drug synthesis (BIODS): In vitro β-glucuronidase inhibitory and in silico studies on 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl aryl carboxylate derivatives
Current study is based on the biology-oriented drug synthesis (BIODS) of 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl aryl carboxylate derivatives 1–26, by treating metronidazole with different aryl and hetero-aryl carboxylic acids in the presence of 1,1'-carbonyl diimidazole (CDI) as a coupling...
| Published in: | European Journal of Medicinal Chemistry |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Elsevier Masson SAS
2017
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84998812010&doi=10.1016%2fj.ejmech.2016.11.031&partnerID=40&md5=937e8fecaed1bd9be8889e93bcbc9b85 |