Synthesis, in vitro α-glucosidase inhibitory activity and molecular docking studies of new thiazole derivatives

Current study based on the synthesis of new thiazole derivatives via “one pot” multicomponent reaction, evaluation of their in vitro α-glucosidase inhibitory activities, and in silico studies. All synthetic compounds were fully characterized by 1H NMR, 13C NMR and EIMS. CHN analysis was also perform...

Full description

Bibliographic Details
Published in:Bioorganic Chemistry
Main Author: Khan K.M.; Qurban S.; Salar U.; Taha M.; Hussain S.; Perveen S.; Hameed A.; Ismail N.H.; Riaz M.; Wadood A.
Format: Article
Language:English
Published: Academic Press Inc. 2016
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84984780886&doi=10.1016%2fj.bioorg.2016.08.010&partnerID=40&md5=3574321f021ec73e9dba5be1355a6478