Syntheses, in vitro evaluation and molecular docking studies of 5-bromo-2-aryl benzimidazoles as α-glucosidase inhibitors
Based on the previous reports on α-glucosidase inhibitory activity of benzimidazole class, we intend to evaluate further this class as potential inhibitors of α-glucosidase enzyme. Thus, in the current study synthesis of 5-bromo-2-aryl benzimidazole derivatives 1–25 was carried out. All the syntheti...
Published in: | Medicinal Chemistry Research |
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Main Author: | |
Format: | Article |
Language: | English |
Published: |
Birkhauser Boston
2016
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Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84979210899&doi=10.1007%2fs00044-016-1614-y&partnerID=40&md5=783f7712e81dcb8af6637a6d3aa7ba17 |