Syntheses, in vitro evaluation and molecular docking studies of 5-bromo-2-aryl benzimidazoles as α-glucosidase inhibitors

Based on the previous reports on α-glucosidase inhibitory activity of benzimidazole class, we intend to evaluate further this class as potential inhibitors of α-glucosidase enzyme. Thus, in the current study synthesis of 5-bromo-2-aryl benzimidazole derivatives 1–25 was carried out. All the syntheti...

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Bibliographic Details
Published in:Medicinal Chemistry Research
Main Author: Arshad T.; Khan K.M.; Rasool N.; Salar U.; Hussain S.; Tahir T.; Ashraf M.; Wadood A.; Riaz M.; Perveen S.; Taha M.; Ismail N.H.
Format: Article
Language:English
Published: Birkhauser Boston 2016
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84979210899&doi=10.1007%2fs00044-016-1614-y&partnerID=40&md5=783f7712e81dcb8af6637a6d3aa7ba17