Synthesis of novel disulfide and sulfone hybrid scaffolds as potent β-glucuronidase inhibitor
Novel series of disulfide and sulfone hybrid analogs (1 −2 0) were synthesized and characterized through EI-MS and 1H NMR and evaluated for β-glucuronidase inhibitory potential. All synthesized analogs except 13 and 15 showed excellent β-glucuronidase inhibitory potential with IC50 value ranging in...
| Published in: | Bioorganic Chemistry |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Academic Press Inc.
2016
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84978792041&doi=10.1016%2fj.bioorg.2016.07.002&partnerID=40&md5=fab601fd5abd5eb3632e5e695647f875 |