Dihydropyrimidones: As novel class of β-glucuronidase inhibitors
Dihydropyrimidones 1–37 were synthesized via a ‘one-pot’ three component reaction according to well-known Biginelli reaction by utilizing Cu(NO3)2·3H2O as catalyst, and screened for their in vitro β-glucuronidase inhibitory activity. It is worth mentioning that amongst the active molecules, compound...
Published in: | Bioorganic and Medicinal Chemistry |
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Main Author: | |
Format: | Article |
Language: | English |
Published: |
Elsevier Ltd
2016
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Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84978791280&doi=10.1016%2fj.bmc.2016.06.002&partnerID=40&md5=ef9bc031727d6ea9efb356f0399856e6 |