Dihydropyrimidones: As novel class of β-glucuronidase inhibitors

Dihydropyrimidones 1–37 were synthesized via a ‘one-pot’ three component reaction according to well-known Biginelli reaction by utilizing Cu(NO3)2·3H2O as catalyst, and screened for their in vitro β-glucuronidase inhibitory activity. It is worth mentioning that amongst the active molecules, compound...

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Bibliographic Details
Published in:Bioorganic and Medicinal Chemistry
Main Author: Ali F.; Khan K.M.; Salar U.; Iqbal S.; Taha M.; Ismail N.H.; Perveen S.; Wadood A.; Ghufran M.; Ali B.
Format: Article
Language:English
Published: Elsevier Ltd 2016
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84978791280&doi=10.1016%2fj.bmc.2016.06.002&partnerID=40&md5=ef9bc031727d6ea9efb356f0399856e6